🧬 Neuro-Glia Interaction in Disease

• Functional analysis of microglia and neurons through targeted genetic modulation

• Real-time visualization of cellular interactions using 2D/3D/4D live-cell imaging platforms

• Quantitative tracking of synaptic dysfunction and structural alterations over time

🔬 Advanced Bio-Imaging Platform 

• Real-time functional analysis of cells using optophysiological assays, including calcium imaging and synaptic vesicle endo/exocytosis

• Spatial and genetic manipulation at the cellular level to decode neuronal circuitry

• Super-resolution imaging for detailed visualization of synaptic structures

• 3D/4D image rendering and quantitative analysis using IMARIS software

🧠 Disease Modeling for Precision Medicine

• Spatial transcriptomic analysis for profiling immune cell distribution and function in disease contexts

• Single-cell RNA sequencing using iPSC-derived brain organoids to dissect cell-type-specific responses

• Integration of multi-omics data to map disease-specific neuroimmune microenvironments